At present, the elderly population in Korea is 14% of the total population and then We has entered an the society of advanced age. Along with this, elderly people with dementia and palsy are also increasing. The demand for elderly nursing homes for elderly people with severe diseases such as dementia and stroke is also increasing, and the existing buildings are being secured by Conversion of existing buildings. However, it is difficult to evacuate and fire due to the out of date of buildings by Conversion of existing buildings. For example, there is a fire in the Indukukwon, Pohang City and Hyosung Geriatric Hospital, Jangseong in Korea, which have changed the use of existing buildings. Many elderly people died in a night fire. It was because of the sandwich panel walls and PVC flooring material produced toxic gas instantly. In this study, we investigated the nursing home that changing the use and established fire prevention of human injury and countermeasure of evacuation. First, the sandwich panels which leading to deaths due to the toxic gas were installed in most nursing home. We recommend the RC, the masonry wall, and the glass fiber panel instead of the sandwich panels, In addition, the PVC flooring is most used in nursing home, the flooring material is considered such as the building stones, the tile, and the yellow soil closing instead of the PVC flooring. Second, we investigated the installation status of fire fighting equipment. As a result, the automatic-emergency open&shut equipment, the smoke ventilator and the evacuation slide were rarely installed. In order to secure the golden time in case of fire and to prevent the asphyxia caused by the toxic gas, the law should be amended to install the equipment.